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Last update: 6/21/06

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Microbial Pathogenesis and Gene Therapy

Mission: To make fundamental advances in microbial pathogenesis and gene therapy in order to contribute to the treatment of infectious and genetic diseases

Translation: Viruses, bacteria and defective genes can all cause diseases and we are looking for key steps in the processes where treatments could intervene.

Contact: David Pintel, Professor of Molecular Biology and Immunology: PintelD@missouri.edu

Burke, Donald

Biochemistry of RNA aptamers and ribozymes; Anti-HIV antiviral therapeutics and the evolution of drug resistance; Macromolecular evolution and the origin of Life

 

Johnson, Marc

Retrovirology, live cell imaging, electron microscopy, cell biology

 

Lorson, Chris

Molecular basis of spinal muscular atrophy; RNA processing; gene therapy

 

Sarafianos, Stefan

Molecular mechanisms of drug resistance and inhibition of HIV, SARS, and other viral and bacterial pathogens.

 

Stewart, George

Regulation of virulence gene expression in Staphylococcus aureus, Fusobacterium necrophorum and Bacillus anthracis

 

Pintel, David

Analysis of eukaryotic gene expression using parvovirus model systems; molecular virology

   

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Life Sciences Center. University of Missouri - Columbia.